MPNN ProGen2 Xlarge CATH42 by InstructPLM

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MPNN ProGen2 Xlarge CATH42 Benchmarks

nn.n% — How the model compares to the reference models: Anthropic Sonnet 3.5 ("so35"), GPT-4o ("gpt4o") or GPT-4 ("gpt4").
MPNN ProGen2 Xlarge CATH42 (InstructPLM/MPNN-ProGen2-xlarge-CATH42)

MPNN ProGen2 Xlarge CATH42 Parameters and Internals

Model Type 
protein design
Additional Notes 
InstructPLM is a protein design model based on ProGen2 and ProteinMPNN. The model is capable of designing protein sequences that conform to specified backbone structures.
Training Details 
Data Sources:
CATH 4.2
LLM NameMPNN ProGen2 Xlarge CATH42
Repository ๐Ÿค—https://huggingface.co/InstructPLM/MPNN-ProGen2-xlarge-CATH42 
Model Size6.6b
Required VRAM13.1 GB
Updated2025-06-01
MaintainerInstructPLM
Model Typeprogen
Model Files  5.0 GB: 1-of-3   5.0 GB: 2-of-3   3.1 GB: 3-of-3
Model ArchitectureProGenForCausalLM
Licenseapache-2.0
Transformers Version4.37.2
Tokenizer ClassiPLMTokenizer
Vocabulary Size30
Torch Data Typefloat16
Activation Functiongelu_new

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Original data from HuggingFace, OpenCompass and various public git repos.
Release v20241227